Artefill

Artefill Injectable Filler - Is It Right For You?

Reviewed by Yael Halaas, MD

Artefill is a long-lasting — maybe even permanent — injectable soft tissue filler. It can put the brakes on your smile lines (nasolabial folds) for a long, long time — maybe even forever.

Artefill was approved by the FDA in October 2006 for the treatment of nasolabial folds and has also been used off-label for lip augmentation, acne scars, and other wrinkles. It bears the distinction of being the only "permanent" soft tissue filler approved for use in the U.S.

What Is Artefill?

Artefill is a hybrid gel filler consisting of millions of synthetic microspheres of polymethylmethacrylate (PMMA) which are suspended in purified bovine (cow) collagen. Artefill also contains a local anesthetic. This takes the edge off by providing pain relief at the same time as the initial injection. Artefill results appear almost immediately.

An allergy test is usually done about a month before treatment because of the bovine collagen in Artefill. If you and your doctor decide on Artefill, the procedure takes approximately 15 minutes to perform and is typically done in the doctor's office. He or she injects the filler beneath your smile lines, plumping them up immediately.

Sometimes more than one treatment session is needed. In these cases, the Artefill treatments are usually performed three to six weeks apart. There is virtually no downtime after Artefill injections.

Artefill vs. Other Soft Tissue Fillers

With other fillers such as Restylane or Juvederm, the ingredients are gradually re-absorbed by the body. By contrast, the microspheres in Artefill are not absorbed by the body. This is why Artefill lasts longer than other fillers on the market. The microspheres can only be removed surgically.

What's more, the microspheres in Artefill also stimulate your body to produce collagen, which is the main structural protein found in your skin. Our collagen supply dwindles with advancing age, often resulting in facial lines, folds and other signs of aging on the face.

Is Artefill Right For You?

Artefill is best if you already know that you like what a soft tissue filler can do for your face. Permanent is great if you are in love with the results, but not so great if you are not. Artefill is best for smile lines; it is not recommended for areas with thinner skin such as crow's feet around the eyes.

Not everyone is a candidate for Artefill injections. Importantly, Artefill has not been tested for safety in pregnant or breastfeeding women, or in women younger than 18. If you have any cysts, pimples, rashes, hives or infection near the injection site, treatment should be postponed.

In addition, tell your doctor if you are taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) because these agents may increase bruising or bleeding risks. Other factors that may affect your Artefill candidacy include history of any other treatment for facial wrinkles in the last six months, UV light therapy to treat skin diseases, and/or use of immunosuppressive therapy. Your doctor should take a thorough medical history before deciding whether Artefill is right for you.

Artefill Risks

Artefill side effects may include redness, swelling, lumpiness, pain or sensitivity at the injection site. Some people experience facial firmness after injection, but this usually resolves over time. Occasionally, there is some mild bruising which can last about three to seven days. Lumps and granulomas may occur with Artefill as well as other soft tissue fillers.

There is always the risk of being unhappy or dissatisfied with the cosmetic results, and this risk is more pronounced when the results are permanent. The best way to minimize your risks and maximize your satisfaction is to choose a qualified, experienced injector and closely follow his or her advice. Board-certified plastic surgeons and facial plastic surgeons are uniquely qualified to use injectables such as Artefill.

Choosing Your Artefill Provider

There are many facial plastic surgeons offering their services, making it hard to know whom to choose. All About Facial Rejuvenation takes the pain out of finding a surgeon by offering you a directory of highly trained facial plastic surgeons who have years of experience performing a range of cosmetic procedures. To find a qualified surgeon near you, click here or on the right side of this page.

Artefill Cost

Artefill injections cost around $1,000 per syringe. Insurers typically do not cover the cost of cosmetic procedures such as Artefill. If the cost is too much to pay all at once, ask your doctor about financing or payment plans. Help may be available.

To view a comparison chart explaining the pros and cons of all available injectables, please click here.



  • Ormsby 50x50

    Marcia V. Ormsby, MD

    Annapolis Aesthetic Surgery, Inc.
    116 Defense Hwy.,
    #500
    Annapolis, MD 21401
    (866) 899-0158


  • Slupchynskyj 58x57

    Oleh Slupchynskyj, MD

    The Aesthetic Institute of New York & New Jersey
    44 E 65th St.
    Suite 1A
    New York, NY 10021
    (888) 492-5439


  • Halaas 58x57

    Yael Halaas, MD, FACS

    60 E. 56th Street
    3rd Floor
    New York, NY 10022
    (877) 831-4250